Research Articles
Structure-Based Drug Design for Cancer Targets: Principles, AI-Driven Methods, and Clinical Applications
This article provides a comprehensive overview of Structure-Based Drug Design (SBDD) and its pivotal role in modern oncology drug discovery.
AI in Oncology Drug Development: Transforming Discovery from Target to Trial in 2025
This article provides a comprehensive analysis of the transformative role of Artificial Intelligence (AI) across the oncology drug development pipeline.
Revolutionizing Oncology: A Comprehensive Guide to Computer-Aided Drug Design (CADD) for Cancer Therapeutics
This article provides a comprehensive overview of Computer-Aided Drug Design (CADD) and its transformative role in accelerating oncology drug discovery.
Liquid vs. Solid: Validating Circulating Tumor DNA Analysis Against the Tissue Biopsy Gold Standard
This article provides a comprehensive review of the validation of circulating tumor DNA (ctDNA) analysis against traditional tissue biopsies in oncology.
Optimization Algorithms for Cancer Biomarker Selection: A Comparative Review of AI and Machine Learning Methods
The selection of optimal biomarkers from high-dimensional biological data is a critical challenge in developing precise cancer diagnostics and therapies.
Validating Pharmacophore Models with Experimental IC50 Values: A Comprehensive Guide for Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on the critical process of validating pharmacophore models through experimental IC50 values.
Comparative Analysis of Mathematical Models for Cancer Treatment Optimization: From Mechanistic Foundations to Clinical Translation
This article provides a comprehensive comparative analysis of mathematical modeling approaches for optimizing cancer treatment.
Beyond BERT: A Comparative Analysis of Sentence Transformers for DNA Sequence Representation in Cancer Genomics
The application of Sentence Transformer models to DNA sequence analysis presents a transformative opportunity in cancer genomics.
Validating Real-Time Oncology Data from EHRs: A Framework for Reliable Real-World Evidence in Cancer Research and Drug Development
This article provides a comprehensive framework for the validation of real-time oncology data extracted from Electronic Health Records (EHRs), tailored for researchers and drug development professionals.
Targeted Therapies vs. Chemotherapy: A Comparative Analysis of Efficacy, Mechanisms, and Future Directions in Oncology
This article provides a comprehensive comparative analysis of traditional chemotherapy and targeted cancer therapies for a professional audience of researchers, scientists, and drug development professionals.