Research Articles
Illuminating the Future of Cancer Therapy: Targeted Light Warriors Against Tumors
Breakthrough in photodynamic therapy using EGFR-targeted photosensitizers encapsulated in Pluronic F127 micelles for precise cancer treatment.
Unlocking Cancer's Master Switches: How Molecular "Superheroes" Are Forged Through Macrocyclization
Discover how macrocyclization enables polypharmacology in cancer treatment, creating multi-target drugs that overcome resistance by simultaneously inhibiting PI3K, mTOR, and PIM pathways.
Theodore Puck: The Unseen Architect of Modern Medicine Who Gave Life to Laboratory Cells
The story of Theodore Puck, the pioneer who revolutionized cell culture and laid the foundation for modern genetics and biotech industry.
The Molecular Trojan Horse: A Triple-Threat Weapon Emerges in the Cancer Fight
Exploring Biotin-SN38-Valproic Acid Conjugates as a targeted cancer therapy approach combining chemotherapy, epigenetic modulation, and precise delivery.
The Invisible Architects: How ATPase Enzymes Rewire Cancer's Survival Blueprint
Exploring how ATPase enzymes are hijacked by cancer cells to fuel metastasis, manipulate pH, and develop drug resistance, with insights into therapeutic strategies.
The Enzyme's Hidden Passport: How CK2α Sneaks into the Cell's Control Center
Discover how CK2α's cryptic nuclear localization signal in its αD helix enables nuclear entry, with implications for cancer therapy.
The Gatekeeper's Nemesis: How OC144-093 Could Revolutionize Epilepsy Treatment
Exploring OC144-093, a novel P-glycoprotein inhibitor that could transform treatment for pharmacoresistant epilepsy by overcoming the blood-brain barrier.
The Secret Keepers: How Molluscs Are Revolutionizing Science and Why Their Care Matters
Exploring how molluscs are revolutionizing scientific research in neuroscience, climate science, and medicine through their unique biological features.
Unlocking Cancer's Defenses: New Combo Therapy Shows Striking Promise Against Aggressive Tumors
Novel DNA-PK inhibitor combined with radiation therapy demonstrates potent synergy against glioblastoma and lung cancer in preclinical studies.
The Silent Threat: Catching Tiny Pancreatic Tumors Before They Strike
Exploring cutting-edge methods to detect and treat small pancreatic head tumors before they become life-threatening.