Exploring the development of prodrug-payloads based on platinum-acridine hybrid agents—a revolutionary approach for precise cancer treatment.
Discover how c-Myc suppresses p21 expression during oestrogen signalling and antioestrogen resistance in human breast cancer cells.
Discover how Hawaii's poha berry (Physalis peruviana) contains powerful compounds that fight inflammation and may help prevent cancer.
Discover how grindstone chemistry enables rapid, solvent-free synthesis of 1,6-naphthyridines for pharmaceutical applications with environmental benefits.
Exploring how synthetic philosophy integrates multiple disciplines to create innovative solutions for combating desertification and global warming.
Explore how molecular dynamics simulations reveal the intricate workings of copper proteins in biology, from DNA binding to cell death mechanisms.
Exploring the cutting-edge science of organometallic compounds as targeted anti-tumor agents that promise more precise cancer treatment with fewer side effects.
Explore the crystal structure of (E)-1-(3,4-methylenedioxy-6-fluorophenyl)-2-nitropropene and its significance in medicine and forensics.
Discover how rhamnose-modified antibodies are transforming cancer immunotherapy through in situ self-assembly techniques for enhanced precision and effectiveness.
Discover how FF-10101, a novel CSF1R inhibitor with unique covalent binding, reprograms tumor-associated macrophages to create an anti-tumor immune environment and enhances cancer immunotherapy.