Research Articles
Pharmacophore Modeling in Oncology: From Virtual Screening to Clinical Candidates
This article provides a comprehensive overview of pharmacophore modeling applications in oncology drug discovery, tailored for researchers and drug development professionals.
Structure-Based Virtual Screening for HER2-Positive Breast Cancer: From Hit Discovery to Clinical Translation
This article provides a comprehensive overview of structure-based virtual screening (SBVS) applications in developing novel therapeutics for HER2-positive breast cancer.
Overcoming False Positives in Virtual Screening: AI and Advanced Strategies for Accelerating Cancer Drug Discovery
This article addresses the critical challenge of false positives in structure-based virtual screening, a major bottleneck in discovering novel oncology therapeutics.
Virtual Screening in Anticancer Drug Discovery: Methods, AI Applications, and Success Stories
This article provides a comprehensive overview of virtual screening (VS) and its transformative role in anticancer drug discovery.
AI in Oncology Drug Development: Transforming Discovery from Target to Trial in 2025
This article provides a comprehensive analysis of the transformative role of Artificial Intelligence (AI) across the oncology drug development pipeline.
Structure-Based Drug Design for Cancer Targets: Principles, AI-Driven Methods, and Clinical Applications
This article provides a comprehensive overview of Structure-Based Drug Design (SBDD) and its pivotal role in modern oncology drug discovery.
Revolutionizing Oncology: A Comprehensive Guide to Computer-Aided Drug Design (CADD) for Cancer Therapeutics
This article provides a comprehensive overview of Computer-Aided Drug Design (CADD) and its transformative role in accelerating oncology drug discovery.
qPCR vs IHC for HER2 Status Determination: A Comprehensive Guide for Precision Oncology
This article provides a comprehensive comparison between reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and immunohistochemistry (IHC) for determining HER2 status in breast cancer.
Validating RNA-seq with RT-qPCR in Cancer Research: A Comprehensive Guide from Bench to Bedside
This article provides a definitive guide for researchers and drug development professionals on validating RNA-seq findings with RT-qPCR in cancer research.
Molecular Alignment in 3D-QSAR: A Comparative Guide to Methods, Applications, and Best Practices for Drug Discovery
This article provides a comprehensive analysis of molecular alignment methodologies central to 3D-QSAR, a critical technique in modern computer-aided drug design.