Research Articles
A Modern Workflow for Mathematical Modeling in Cancer Treatment Optimization: From Biological Principles to Clinical Translation
This article provides a comprehensive guide to the workflow of mathematical modeling for optimizing cancer treatment, tailored for researchers, scientists, and drug development professionals.
Validating Cancer Biomarkers with Real-Time PCR: Protocols, Optimization, and Clinical Translation
This article provides a comprehensive guide for researchers and drug development professionals on implementing real-time quantitative PCR (qPCR) for robust cancer biomarker validation.
Digital PCR in Circulating Tumor DNA Analysis: Advanced Methods for Sensitive Detection and Clinical Application
This article provides a comprehensive technical overview of digital PCR (dPCR) methodologies for analyzing circulating tumor DNA (ctDNA), a cornerstone of liquid biopsy in precision oncology.
Next-Generation Sequencing in Cancer Diagnostics: A Comprehensive Guide for Researchers and Drug Developers
Next-generation sequencing (NGS) has fundamentally transformed oncology, enabling comprehensive genomic profiling that drives precision medicine.
From Sequence to Diagnosis: A Practical Guide to Machine Learning for DNA-Based Cancer Detection
This article provides a comprehensive guide for researchers and drug development professionals on the practical implementation of machine learning (ML) for cancer detection using DNA sequence data.
3D-QSAR in Cancer Drug Discovery: Techniques for Optimizing Anticancer Compounds
This article provides a comprehensive overview of 3D Quantitative Structure-Activity Relationship (3D-QSAR) techniques and their pivotal role in optimizing anticancer compounds.
A Practical Guide to Pharmacophore-Based Virtual Screening: From Core Concepts to Experimental Validation
This article provides a comprehensive guide to pharmacophore-based virtual screening (VS) for researchers and drug development professionals.
A Comprehensive 2025 Guide: Molecular Dynamics Simulations for Protein-Ligand Complexes from Setup to Validation
This article provides a current and comprehensive methodology for conducting molecular dynamics (MD) simulations of protein-ligand complexes, tailored for researchers and professionals in drug development.
Molecular Docking in Breast Cancer Drug Discovery: A Practical Guide from Target Identification to Clinical Translation
This comprehensive review explores the practical application of molecular docking in breast cancer research, addressing the needs of researchers and drug development professionals.
AI-Powered Virtual Screening: Computational Protocols Revolutionizing Anticancer Drug Discovery
This comprehensive review explores the transformative role of computational virtual screening protocols in accelerating anticancer drug discovery.