Exploring how multifunctional polymeric nanoparticles are revolutionizing cancer immunotherapy through advanced RNA delivery systems.
Discover how oxidative stress hijacks the cellular regulator Pin1 through lipid electrophiles, contributing to diseases like cancer and Alzheimer's.
Exploring how pyrido[2,3-d]pyrimidines are being engineered as precision anticancer agents through medicinal chemistry approaches.
Exploring how polymer-drug conjugates are transforming medicine by targeting novel molecular pathways with precision drug delivery.
Exploring the invisible crisis of contaminated water in oil industry operations, detection methods, and emerging solutions.
Exploring the revolutionary click chemistry approach to create potent triazole-tethered isatin conjugates for cancer treatment and beyond.
Discover how SMAPs (Small Molecule Activators of PP2A) can disarm KRAS by awakening the dormant tumor suppressor PP2A in KRAS-driven cancers.
Exploring how molecular conformation dynamics are transforming cancer drug design, with focus on M1 aminopeptidase inhibitors.
Exploring how p53's tetrameric structure binds DNA to regulate genes critical for cancer prevention, with recent structural breakthroughs and therapeutic implications.
Discover how elacestrant, the first oral SERD approved for ER-positive, HER2-negative breast cancer with ESR1 mutations, is transforming treatment paradigms.