Research Articles
The Magic Bullet Quest: How Platinum Drugs Revolutionized Cancer Treatment
Explore the fascinating journey of platinum-based anticancer drugs from accidental discovery to revolutionary cancer treatment and future innovations.
Disarming Cancer's Defenses: The Story of Lomeguatrib
Explore how lomeguatrib is revolutionizing cancer treatment by overcoming chemotherapy resistance through MGMT inhibition.
A One-Two Punch: Resensitizing a Deadly Brain Cancer to Chemotherapy
Discover how bortezomib sensitizes glioblastoma with unmethylated MGMT promoter to temozolomide-chemotherapy through MGMT depletion and abrogated autophagy flux
The Double-Edged Sword: Protecting the Heart in the Fight Against Cancer
Exploring innovative strategies to prevent and treat anthracycline-induced cardiotoxicity while preserving cancer treatment efficacy
A Smarter Strike on Cancer: The One-Two Punch That Targets Tumors and Unleashes Its Payload On Command
Discover how scientists are creating smart cancer drugs that target tumors with precision and release chemotherapy only inside cancer cells, reducing side effects.
The Double-Edged Sword: When Life-Saving Chemotherapy Turns Toxic
Understanding anthracycline extravasation - a serious complication of cancer treatment where chemotherapy drugs leak into surrounding tissues, causing severe damage.
The Trojan Horse: How Scientists Are Tricking Cancer Cells into Consuming Their Own Chemo
Explore how Cathepsin B-cleavable cyclopeptidic prodrugs act as molecular Trojan horses to deliver chemotherapy precisely to cancer cells, reducing side effects.
Sweet Targeting: How Sugar-Coated Cancer Drugs Are Revolutionizing Chemotherapy
Discover how glycan-based paclitaxel prodrugs target cancer cells through glucose transporters for more precise chemotherapy with fewer side effects.
Beyond Platinum: The Rise of Ruthenium in the Cancer Arms Race
Exploring how ruthenium complexes are emerging as promising alternatives to platinum-based cancer therapies with improved targeting and reduced side effects.
Metal-Containing Macromolecules: The Next Generation of Cancer Warriors
Exploring how metal-containing macromolecules are revolutionizing cancer treatment with targeted therapy and reduced side effects.